Health / Medical Topics

    NOTCH3 Gene

    This gene plays a role in both intercellular signaling and cell fate determination. (NCI Thesaurus)




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    Human NOTCH2 wild-type allele is located within 1p13-p11 and is approximately 158 kb in length. This allele, which encodes neurogenic locus notch…
    This gene plays a role in cell-cell signaling.
    Human NOTCH1 wild-type allele is located in the vicinity of 9q34.3 and is approximately 51 kb in length. This allele, which encodes…
    This gene is involved in intercellular signal transduction that plays a key role in development.
    The Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the…
    The free carboxy-terminal intracellular domain (ICD) of a notch family protein, which is a product of regulated intramembrane proteolysis mediated by the…

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