| Health / Medical Topics |
NPM1/RARA Short Fusion Protein
A fusion protein (520 aa, ~57 kDa) encoded by the NPM1/RARA short fusion gene. This protein is comprised of the N-terminus of the nucleophosmin protein fused to the DNA-binding domain, ligand binding domain and coactivator recognition site from the retinoic acid receptor alpha protein. (NCI Thesaurus)
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A fusion gene (~1.9 kb) that results from a chromosomal translocation t(5;17)(q35;q21) which fuses the first 442 nucleotides of the NPM1 gene…
A fusion protein (563 aa, ~63 kDa) encoded by the NPM1/RARA long fusion gene. This protein is comprised of the N-terminus of…
A fusion gene (~2.1 kb) that results from a chromosomal translocation t(5;17)(q35;q21) which fuses the first 484 nucleotides of the NPM1 gene…
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A fusion gene that results from a chromosomal translocation t(2;5)(p23;q35) which fuses the first 4 exons of the NPM1 gene with the…
Human NPM1 wild-type allele is located in the vicinity of 5q35 and is approximately 24 kb in length. This allele, which encodes…
