Health / Medical Topics |
Nucleoporin
Definition 1
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The proteins encoded by these genes function in the nuclear transport of protein and RNA. (from LocusLink 4928, OMIM 601021) (NCI Thesaurus)
Definition 2
Proteins that form the structure of the nuclear pore. They are involved in active, facilitated and passive transport of molecules in and out of the cell nucleus. (NLM, Medical Subject Headings)
YOU MAY ALSO LIKE
The nuclear contents other than the nucleolus.
A human nuclear matrix protein with demonstrated immunohistochemical staining differences between benign and malignant prostate tissue.
Within most types of eukaryotic CELL NUCLEUS, a distinct region, not delimited by a membrane, in which some species of rRNA (RNA,…
The irregular network or rows of fine ribonucleoprotein granules or microfilaments forming most of the nucleolus.
A synthetic, multivalent, lysine-rich, pseudopeptide and nucleolin antagonist with potential anti-angiogenic, antineoplastic and pro-apoptotic activities. Upon administration, IPP-204106N antagonizes nucleolin leading to…
Nucleolin (710 aa, ~77 kDa) is encoded by the human NCL gene. This protein is involved in both chromatin decondensation and ribosome…