| Health / Medical Topics |
Nucleotide Transition Abnormality
A point mutation that involves the substitution of a pyrimidine base for a different pyrimidine base or substitution of a purine base for a different purine base. Nucleotide transitions do not change the purine-pyrimidine orientation of a DNA sequence. A nucleotide transition abnormality may be heritable or occur somatically. (NCI Thesaurus)
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