Health / Medical Topics

    Nucleotide Transversion Abnormality

    A point mutation that involves the substitution of a pyrimidine base for a purine base or substitution of a purine base for a pyrimidine base. Nucleotide transversions change the purine-pyrimidine orientation of a DNA sequence. A nucleotide transversion abnormality may be heritable or occur somatically. (NCI Thesaurus)




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