| Health / Medical Topics |
NUP214/ABL1 Fusion Gene Variant 1
A fusion gene that results from a chromosomal rearrangement of 9q34 which fuses most of the NUP214 gene with intron 1 of the ABL1 gene. This fusion is associated with T-cell acute lymphoblastic leukemia. (NCI Thesaurus)
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A fusion protein encoded by the NUP214/ABL1 fusion gene variant 1. This protein is comprised of the N-terminal portion of the nuclear…
A fusion protein (~239 kDa) encoded by the NUP214/ABL1 fusion gene variant 2. This protein is comprised of approximately half of the…
Human NUP214 wild-type allele is located in the vicinity of 9q34.1 and is approximately 108 kb in length. This allele, which encodes…
This gene plays a critical role in nuclear transport and docking regulation. Alterations in the gene have been associated with several cancers…
Human NUP107 wild-type allele is located in the vicinity of 12q15 and is approximately 56 kb in length. This allele, which encodes…
This gene is involved in the assembly of the nuclear pore complex.
