Health / Medical Topics |
NUP98/HOXD13 Fusion Gene
A fusion gene (~1.9 kb) that results from a chromosomal translocation t(2;11)(q31;p15) which fuses the first twelve exons of the NUP98 gene with exon 2 of the HOXD13 gene. This rearrangement is associated with acute myeloid leukemia. (NCI Thesaurus)
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A fusion protein encoded by the NUP98/HOXC13 fusion gene. This protein is comprised of the N-terminal nucleoporin GLFG repeat domains of the…
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