Health / Medical Topics |
O6-Alkylguanine-DNA Alkyltransferase Inhibitor
Any substance that inhibits O6-Alkylguanine-DNA alkyltransferase, a DNA repair enzyme that catalyzes the removal of alkyl groups from DNA. Inhibition of O6-Alkylguanine-DNA alkyltransferase increases the effectiveness of DNA alkylating agents. (NCI Thesaurus)
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