Health / Medical Topics

    Observed Volume of Distribution of Absorbed Fraction

    Definition 1

    The observed volume of distribution of the absorbed fraction based on the terminal phase, where F equals the fraction of dose absorbed. (NCI Thesaurus)

    Definition 2

    The volume of distribution associated with the terminal slope following extravascular administration divided by the fraction of dose absorbed, calculated using the observed value of the last non-zero concentration. (NCI Thesaurus/CDISC)




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