Library / English Dictionary

ONCOGENE

Pronunciation (US):

(GB):

 I. (noun) 

Sense 1

Meaning:

A gene that disposes normal cells to change into cancerous tumor cells

Synonyms:

oncogene; transforming gene

Classified under:

Nouns denoting body parts

Hypernyms ("oncogene" is a kind of...):

cistron; factor; gene ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity)

Credits

 Context examples: 

This allele, which encodes Myb proto-oncogene protein, plays a role in both the modulation of transcription by RNA polymerase II and differentiation of hematopoietic progenitor cells.

(MYB wt Allele, NCI Thesaurus)

Myc proto-oncogene protein (439 aa, ~49 kDa) is encoded by the human MYC gene.

(Myc Proto-Oncogene Protein, NCI Thesaurus)

NMYC interactor (NMI) is a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif.

(NMYC Interactor, NCI Thesaurus/LocusLink)

Oncogenes may cause the growth of cancer cells.

(Oncogene, NCI Dictionary)

Human v-abl Abelson murine leukemia viral oncogene homolog 1 (ABL1) gene, located at 9q34.1, encodes proto-oncogene tyrosine-protein kinase ABL1 protein.

(Oncogene ABL1, NCI Thesaurus)

Any DNA sequence alteration process occurring in a proto-oncogene, resulting in loss of regulation of the gene product, and predisposing the cell to neoplastic transformation.

(Oncogene Activation Process, NCI Thesaurus)

Recombination of the wild-type allele with the RET proto-oncogene wild-type allele is found in papillary thyroid carcinomas.

(NCOA4 wt Allele, NCI Thesaurus)

N-myc proto-oncogene protein (464 aa, ~50 kDa) is encoded by the human MYCN gene.

(N-Myc Proto-Oncogene Protein, NCI Thesaurus)

This allele, which encodes myc proto-oncogene protein, plays a role in the regulation of transcription by RNA polymerase II.

(MYC wt Allele, NCI Thesaurus)

This allele, which encodes L-myc-1 proto-oncogene protein, is involved in modulation of transcription by RNA polymerase II.

(MYCL1 wt Allele, NCI Thesaurus)