Health / Medical Topics

    Oncogene MYCN

    Human Oncogene NMYC is a mutated variant of NMYC Gene (MYC Family), which encodes two nuclear N-MYC Proteins from the same mRNA; both are phosphorylated, exceptionally unstable and bind to single- and double-stranded DNA. N-MYC is a likely heterodimeric bZIP transcription factor with MAX; efficient DNA binding requires dimerization with another bHLH protein. NMYC amplification is associated with oncogenic transformation. Oncogene NMYC disrupts normal cell function. (NCI Thesaurus)




    YOU MAY ALSO LIKE

    A viral and cellular gene. A proto-oncogene, identified in several avian tumors, encoding a nuclear protein with a leucine zipper motif. …
    Human Oncogene MYB is a mutated variant of MYB Gene, which encodes 6 alternative isoforms of 640 aa 72-kDa nuclear c-MYB protein,…
    The MET oncogene is derived from a chromosomal rearrangement involving the MET and TPR (translocated promoter region) loci and is a cloned…
    Human Oncogene MCF2 is a mutated variant of widely expressed MCF2 Gene, which encodes 4 alternative variants of 66-kDa MCF2 (DBL) p66…
    Oncogene MAX is a member of the MYC gene family. The MAX gene encodes a bHLH/ZIP protein that forms a heterodimer with…
    Human Oncogene LMYC is a mutated variant of LMYC Gene (MYC Family), which encodes L-MYC Protein, a bZIP transcription factor that binds…

    © 1991-2023 The Titi Tudorancea Bulletin | Titi Tudorancea® is a Registered Trademark | Terms of use and privacy policy
    Contact