| Library / English Dictionary |
OOCYTE
| Pronunciation (US): |  | (GB): | |
I. (noun)
Sense 1
Meaning:
A female gametocyte that develops into an ovum after two meiotic divisions
Classified under:
Hypernyms ("oocyte" is a kind of...):
gametocyte (an immature animal or plant cell that develops into a gamete by meiosis)
Context examples:
Both GDF9 mRNA and protein are abundantly expressed in oocytes of primary follicles in human ovary, suggesting that the GDF9 transcript is translated at this early stage of folliculogenesis.
(Growth Differentiation Factor 9, NCI Thesaurus)
This strain is commonly used in the generation of transgenic mice due to the fact that the pronuclei of FVB/N fertilized oocytes are prominent, which allows for ease of microinjection.
(FVB/N Mouse, NCI Thesaurus)
This communication pathway is derived from granulosa cells and another structure in the ovary called the oocyte, or immature egg cell.
(Study solves ovarian cell mystery, shedding new light on reproductive disorders, NIH)
Tissue comprised of specialized cells and intercellular matrix, aggregated according to genetically determined spatial relationships in order to carry out the functions of production and ovulation of oocytes and the production and secretion of hormones.
(Ovarian Tissue, NCI Thesaurus)
Expressed in oocytes and blastocysts by human GNB2 Gene, 340-aa 37-kDa Guanine Nucleotide Binding Protein Beta 2 is a heterotrimeric G protein beta subunit with 7 WD repeats and involved in transmembrane signaling as a transducer that regulates G protein alpha subunits and integrates signals between receptors and effector proteins.
(Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-2, NCI Thesaurus)
The granulosa cells extend cytoplasmic processes to form gestational gap-junction-like unions with the plasma membrane of the oocyte.
(Ovarian Granulosa Cell, NCI Thesaurus)
Activation of cyclin B-Cdc2 causes breakdown of the germinal vesicle and the initiation of oocyte maturation.
(Oocyte Maturation Pathway, NCI Thesaurus/BIOCARTA)
The resumption of meiosis is stimulated by progesterone, which carries the oocyte through two consecutive M-phases (MI and MII) to a second arrest at MII.
(Oocyte Meiosis Pathway, NCI Thesaurus/KEGG)
The oocyte and its single layer of ovarian granulosa cells make up a primary follicle.
(Ovarian Granulosa Cell, NCI Thesaurus)
The key activity driving meiotic progression is the MPF (maturation-promoting factor), a heterodimer of CDC2 (cell division cycle 2 kinase) and cyclin B. In PI-arrested oocytes, MPF is initially inactive and is activated by the dual-specificity CDC25C phosphatase as the result of new synthesis of Mos induced by progesterone.
(Oocyte Meiosis Pathway, NCI Thesaurus/KEGG)
