| Health / Medical Topics |
Oral Milataxel
An orally bioavailable taxane with potential antineoplastic activity. Upon oral administration, milataxel and its major active metabolite M-10 bind to and stabilize tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, milataxel appears to be a poor substrate for the multidrug resistance (MDR) membrane-associated P-glycoprotein (P-gp) efflux pump and may be useful for treating multidrug-resistant tumors. (NCI Thesaurus)
YOU MAY ALSO LIKE
An orally bioavailable microencapsulated formulation of diindolylmethane, an indole phytonutrient found in cruciferous vegetables, with estrogen-modulating, antiandrogenic, and potential antineoplastic activities. As…
A microbiology subdiscipline concerned with microorganisms of the buccal cavity.
A dentist specializing in the diagnosis and non-surgical management of medically-related disorders or conditions affecting the oral and maxillofacial region.
A pharmacological medication intended for administration through the mouth.
A chronic, autoimmune inflammatory condition of the mucous membranes in the oral cavity that affects approximately two percent of the population and…
A white patch or plaque on the oral mucosa that cannot be characterized clinically or pathologically as any other disease. The diagnosis…
