| Health / Medical Topics |
Oral Sodium Phenylbutyrate
An orally active derivative of the short-chain fatty acid butyrate with potential antineoplastic activity. 4-Phenylbutyrate inhibits histone deacetylase, resulting in cell cycle gene expression modulation, reduced cell proliferation, increased cell differentiation, and apoptosis. This agent also initiates fragmentation of genomic DNA, resulting in decreased DNA synthesis and the inhibition of tumor cell migration and invasion. (NCI Thesaurus)
YOU MAY ALSO LIKE
The introduction of a substance to the mouth or into the gastrointestinal tract by the way of the mouth, usually for systemic…
An aqueous solution composed of glucose and electrolytes, including sodium, potassium, chloride, magnesium, and phosphorus, with dehydration preventative and rehydration activities. Upon…
A suspension composed of active and/or inert ingredient(s) that requires reconstitution and is intended oral administration.
A powder intended for administration through the mouth.
A vaccine that contains live attenuated polio virus. It is administered orally as polio prophylaxis in many areas of the world, but…
An oral preparation of picoplatin, a third generation platinum compound with antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA,…
