| Health / Medical Topics |
Organic Cation Transporter-Like 2 Protein
Encoded by human SLC22A1L Gene (Polyspecific Transporter/Multidrug Resistance Family), 424-amino acid Organic Cation Transporter-Like 2 Protein has ten transmembrane segments. Highest expression occurs in liver, heart, and kidney. The SLC22A1L organic cation transporter protein is localized on the apical surface of renal proximal tubules and appears to confer resistance/transport activity to chloroquine and quinidine-related compounds. Renal epithelial cell apical and basolateral polyspecific organic-cation transporters mediate excretion of endogenous and exogenous compounds. (from OMIM and NCI) (NCI Thesaurus)
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