Health / Medical Topics

    Ovarian Sertoli-Leydig Cell Tumor

    Definition 1

    A benign or malignant sex cord-stromal tumor arising from the ovary. It is characterized by the presence of neoplastic Leydig cells. Signs and symptoms include hirsutism, menorrhagia and metrorrhagia. It may be associated with trisomy 8. (NCI Thesaurus)

    Definition 2

    A rare type of ovarian tumor in which the tumor cells secrete a male sex hormone. This may cause virilization (the appearance of male physical characteristics in females). (NCI Dictionary)




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