| Health / Medical Topics |
Pantothenate Kinase-Associated Neurodegeneration
A rare autosomal recessive inherited disorder caused by mutations in the PANK2 gene. It is characterized by abnormal accumulation of iron in the basal ganglia. Signs and symptoms include progressive motor disturbances, muscle spasm and rigidity, dysarthria, mental deterioration, and behavioral changes. (NCI Thesaurus)
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