| Health / Medical Topics |
PARK2 wt Allele
Human PARK2 wild-type allele is located within 6q25.2-q27 and is approximately 1459 kb in length. This allele, which encodes E3 ubiquitin-protein ligase parkin, may be involved in the modulation of ubiquitination. Mutation of the gene is associated with Parkinson disease and may affect the development or progression of ovarian cancer. (NCI Thesaurus)
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