| Health / Medical Topics |
PAX3/FOXO1 Fusion Gene
A fusion gene (~3.2 kb) that results from a chromosomal translocation t(2;13)(q35;q14) which fuses intron 7 of the PAX3 gene with intron 1 of the FOXO1 gene. This rearrangement is associated with alveolar rhabdomyosarcoma. (NCI Thesaurus)
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Human PAX3 wild-type allele is located within 2q35-q37 and is approximately 99 kb in length. This allele, which encodes paired box gene…
This gene plays a role in the transcriptional activation of target genes. It is involved in melanogenesis, neurogenesis and skeletal muscle…
Human PAX2 wt allele is located in the vicinity of 10q24.31 and is approximately 84 kb in length. This allele, which encodes…
This gene is involved in gene expression and cellular proliferation.
