| Health / Medical Topics |
PAX3/FOXO1 Fusion Protein
A fusion protein (836 aa, ~92 kDa) encoded by the PAX3/FOXO1 fusion gene. This protein is comprised of the N-terminal DNA binding domain of paired box protein Pax-3 and the C-terminal transactivation domain of forkhead box protein O1. (NCI Thesaurus)
YOU MAY ALSO LIKE
A fusion gene (~3.2 kb) that results from a chromosomal translocation t(2;13)(q35;q14) which fuses intron 7 of the PAX3 gene with intron…
A synthetic peptide vaccine based on the sequences of a translocation mutation of 2 transcriptional factor genes, PAX3 and FKHR. PAX3/FKHR fusion…
An antisense oligonucleotide targeting mRNA of the chimeric PAX3/FKHR fusion gene, an oncogenic transcriptional activator found in rhabdomyosarcomas. PAX3/FKHR antisense oligonucleotide…
Human PAX3 wild-type allele is located within 2q35-q37 and is approximately 99 kb in length. This allele, which encodes paired box gene…
This gene plays a role in the transcriptional activation of target genes. It is involved in melanogenesis, neurogenesis and skeletal muscle…
Human PAX2 wt allele is located in the vicinity of 10q24.31 and is approximately 84 kb in length. This allele, which encodes…
