| Health / Medical Topics |
PAX3/NCOA1 Fusion Gene
A fusion gene that results from a rearrangement of chromosome 2 which fuses exon 6 of the PAX3 gene to either exon 12 of the NCOA1 gene. This rearrangement is associated with rare variants of alveolar rhabdomyosarcoma. (NCI Thesaurus)
YOU MAY ALSO LIKE
A fusion protein encoded by the PAX3/FOXO4 fusion gene. This protein is comprised of the N-terminal DNA binding domain of paired box…
A fusion gene that results from a rearrangement involving chromosome 2 and the X chromosome which fuses the 5' portion of the…
A fusion protein (836 aa, ~92 kDa) encoded by the PAX3/FOXO1 fusion gene. This protein is comprised of the N-terminal DNA binding…
A fusion gene (~3.2 kb) that results from a chromosomal translocation t(2;13)(q35;q14) which fuses intron 7 of the PAX3 gene with intron…
A synthetic peptide vaccine based on the sequences of a translocation mutation of 2 transcriptional factor genes, PAX3 and FKHR. PAX3/FKHR fusion…
An antisense oligonucleotide targeting mRNA of the chimeric PAX3/FKHR fusion gene, an oncogenic transcriptional activator found in rhabdomyosarcomas. PAX3/FKHR antisense oligonucleotide…
