| Health / Medical Topics |
PAX5 wt Allele
Human PAX5 wild-type allele is located in the vicinity of 9p13 and is approximately 201 kb in length. This allele, which encodes paired box gene Pax-5 protein, is involved in transcriptional activation during B-cell differentiation, neural development and spermatogenesis. In some lymphomas, the expression of the wild-type allele is elevated as a result of a translocation t(9;14)(p13;q32). (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene is involved in the transcriptional regulation of target genes. It plays a role in B-cell differentiation, neural development and…
A fusion protein encoded by the PAX3/NCOA1 fusion gene. This protein is comprised of the N-terminal DNA binding domain of paired box…
A fusion gene that results from a rearrangement of chromosome 2 which fuses exon 6 of the PAX3 gene to either exon…
A fusion protein encoded by the PAX3/FOXO4 fusion gene. This protein is comprised of the N-terminal DNA binding domain of paired box…
A fusion gene that results from a rearrangement involving chromosome 2 and the X chromosome which fuses the 5' portion of the…
A fusion protein (836 aa, ~92 kDa) encoded by the PAX3/FOXO1 fusion gene. This protein is comprised of the N-terminal DNA binding…
