PAX7/FOXO1 Fusion Gene

A fusion gene (~2.5 kb) that results from a chromosomal translocation t(1;13)(p36;q14) which fuses intron 7 of the PAX7 gene with intron 1 of the FOXO1 gene. This rearrangement is associated with alveolar rhabdomyosarcoma and rare cases of embryonal rhabdomyosarcoma. (NCI Thesaurus)

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PAX7 wt Allele

Human PAX7 wild-type allele is located within 1p36.2-p36.12 and is approximately 105 kb in length. This allele, which encodes paired box gene…

PAX7 Gene

This gene plays a role in the transcriptional regulation of target genes. It is involved in pattern formation during embryogenesis.

PAX6 wt Allele

Human PAX6 wild-type allele is located in the vicinity of 11p13 and is approximately 29 kb in length. This allele, which encodes…

PAX6 Gene

This gene plays a role in transcriptional regulation.

PAX5 wt Allele

Human PAX5 wild-type allele is located in the vicinity of 9p13 and is approximately 201 kb in length. This allele, which encodes…

PAX5 Gene

This gene is involved in the transcriptional regulation of target genes. It plays a role in B-cell differentiation, neural development and…