| Health / Medical Topics |
PAX8/PPARG Fusion Gene
A fusion gene that results from a chromosomal translocation t(2;3)(q13;p25) which fuses exon 7, 8 or 9 of the PAX8 gene with exons 1-6 of the PPARG gene. This rearrangement is associated with both thyroid follicular adenoma and thyroid follicular carcinoma. (NCI Thesaurus)
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Human PAX8 wild-type allele is located in the vicinity of 2q13 and is approximately 63 kb in length. This allele, which encodes…
This gene is involved in thyroid development and transcriptional regulation.
A fusion protein (828 aa, ~90 kDa) encoded by the PAX7/FOXO1 fusion gene. This protein is comprised of the N-terminal DNA binding…
A fusion gene (~2.5 kb) that results from a chromosomal translocation t(1;13)(p36;q14) which fuses intron 7 of the PAX7 gene with intron…
Human PAX7 wild-type allele is located within 1p36.2-p36.12 and is approximately 105 kb in length. This allele, which encodes paired box gene…
This gene plays a role in the transcriptional regulation of target genes. It is involved in pattern formation during embryogenesis.
