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Pazopanib
Definition 1
A small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. (NCI Thesaurus)
Definition 2
A drug that is used to treat kidney cancer and is being studied in the treatment of other types of cancer. It may prevent the growth of new blood vessels that tumors need to grow. It is a type of protein tyrosine kinase inhibitor and a type of antiangiogenesis agent. (NCI Dictionary)
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