Pazopanib hydrochloride

Pronunciation

Definition 1

A drug used to treat advanced renal cell carcinoma, which is the most common type of kidney cancer. It is also used to treat advanced soft tissue sarcoma that has been treated with other anticancer drugs. It is being studied in the treatment of other types of cancer. Pazopanib hydrochloride may prevent the growth of new blood vessels that tumors need to grow. It is a type of protein tyrosine kinase inhibitor and a type of antiangiogenesis agent. Also called GW786034 and Votrient. (NCI Dictionary)

Definition 2

The hydrochloride salt of a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits vascular endothelial growth factor receptors (VEGFR)-1, -2 and -3, c-kit and platelet derived growth factor receptor (PDGF-R), which may result in inhibition of angiogenesis in tumors in which these receptors are upregulated. (NCI Thesaurus)

Definition 3

A drug that is used to treat kidney cancer and is being studied in the treatment of other types of cancer. It may prevent the growth of new blood vessels that tumors need to grow. It is a type of protein tyrosine kinase inhibitor and a type of antiangiogenesis agent. (NCI Dictionary)

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