PC-12

Definition 1

PC-12 adheres poorly to plastic, and tends to grow in small clusters. Attachment is improved by using collagen coated flasks. (NCI Thesaurus)

Definition 2

A cell line derived from a pheochromocytoma of the rat adrenal medulla. PC12 cells stop dividing and undergo terminal differentiation when treated with nerve growth factor, making the line a useful model system for neuronal differentiation. (NLM, Medical Subject Headings)

Definition 3

cell line established from a rat pheochromocytoma; has many properties in common with primary sympathetic neurons and chromaffin cell cultures; used primarily as a neuron model. (NIH CRISP Thesaurus)

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