| Health / Medical Topics |
PCSK7 wt Allele
Human PCSK7 wild-type allele is located within 11q23-q24 and is approximately 28 kb in length. This allele, which encodes proprotein convertase subtilisin/kexin type 7 protein, plays a role in the modulation of protein processing. A chromosomal translocation t(11;14)(q23;q32) of this gene and the IGH locus is associated with mediastinal large cell lymphoma. (NCI Thesaurus)
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