| Health / Medical Topics |
PDGFRA Gene Amplification
A molecular genetic abnormality indicating the presence of multiple copies of the PDGFRA (platelet-derived growth factor receptor, alpha polypeptide) gene. (NCI Thesaurus)
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This gene plays a role in mitogenic activities affecting mesenchymal cells and is involved in receptor tyrosine kinase signal transduction.
Human PDGFC wild-type allele is located in the vicinity of 4q23 and is approximately 211 kb in length. This allele, which encodes…
This gene plays a role in growth factor signaling.
Human PDGFB wild-type allele is located in the vicinity of 22q13.1 and is approximately 22 kb in length. This allele, which encodes…
This gene is involved in cellular growth and proliferation. It is also plays a role in intercellular signaling.
Human PDGFA wild-type allele is located within 7p22 and is approximately 22 kb in length. This allele, which encodes platelet-derived growth factor…
