PDGFRA wt Allele

Human PDGFRA wild-type allele is located within 4q11-q13 and is approximately 69 kb in length. This allele, which encodes alpha platelet-derived growth factor receptor protein, plays a role in mitogenesis for cells of mesenchymal origin. (NCI Thesaurus)

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PDGFRA Protein Variant

A variation in the amino acid sequence for the platelet-derived growth factor receptor alpha protein.

PDGFRA Gene Rearrangement

Rearrangement of the PDGFRA gene, resulting in the formation of a fusion transcript and aberrant tyrosine kinase activity. It has been described…

PDGFRA Gene Mutation

A molecular genetic abnormality indicating the presence of a mutation in the PDGFRA (platelet-derived growth factor receptor, alpha polypeptide) gene on chromosome…

PDGFRA Gene Amplification

A molecular genetic abnormality indicating the presence of multiple copies of the PDGFRA (platelet-derived growth factor receptor, alpha polypeptide) gene.

PDGFRA Gene

This gene plays a role in mitogenic activities affecting mesenchymal cells and is involved in receptor tyrosine kinase signal transduction.

PDGFC wt Allele

Human PDGFC wild-type allele is located in the vicinity of 4q23 and is approximately 211 kb in length. This allele, which encodes…