PDGFRL wt Allele

Human PDGFRL wild-type allele is located within 8p22-p21.3 and is approximately 66 kb in length. This allele, which encodes platelet-derived growth factor receptor-like protein, plays a putative role in the inhibition of cell growth and proliferation. Loss of PDGFRL gene function is associated with several types of cancer including colorectal cancers, hepatocellular carcinomas and non-small cell lung carcinomas. (NCI Thesaurus)

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PDGFRL Gene

This gene may play a role in the negative regulation of cell growth.

PDGFRB/MYO18A Fusion Gene

A fusion gene that results from a chromosomal translocation t(5;17)(q33-34;q11.2) which fuses exon 9 of the PDGFRB gene to exon 41 of…

PDGFRB wt Allele

Human PDGFRB wild-type allele is located within 5q31-q32 and is approximately 42 kb in length. This allele, which encodes beta platelet-derived growth…

PDGFRB Gene Rearrangement

Rearrangement of the PDGFRB gene, resulting in the formation of a fusion transcript and aberrant tyrosine kinase activity. It has been described…

PDGFRB Gene

This gene plays a role in mitogenic activities affecting mesenchymal cells and a translocation in the gene results in chronic myelomonocytic…

PDGFRA wt Allele

Human PDGFRA wild-type allele is located within 4q11-q13 and is approximately 69 kb in length. This allele, which encodes alpha platelet-derived growth…