Health / Medical Topics

    PEA3

    PEA3 is a member of the ETS-related transcription factor family and contains a DNA-binding ETS domain and an N-terminal acidic domain. PEA3 appears to bind to the core consensus sequence GGAA recognized by other ETS proteins. PEA3 is widely expressed (though not in normal lymphocytes) and is especially high in brain and placenta. (from OMIM 601600 and NCI) (NCI Thesaurus)




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