| Health / Medical Topics |
Pegylated Anti-GFR Antibody Fragment
A pegylated, cross-linked, humanized divalent-Fab' antibody fragment directed against vascular endothelial growth factor receptor-2 (VEGFR-2) with potential antiangiogenic and antitumor activities. Pegylated anti-GFR antibody fragment binds to and inhibits VEGFR-2, which may inhibit angiogenesis and tumor cell proliferation. Multivalent Fab' antibody fragments may exhibit improved retention and internalization properties compared to their parent IgGs. (NCI Thesaurus)
YOU MAY ALSO LIKE
A pegylated, recombinant, human growth hormone (GH) structural analog with GH receptor antagonist activity. As a GH analog, the structure of pegvisomant…
A drug used to treat melanoma and hepatitis C. It is also being studied in the treatment of other types of…
A drug used to treat hepatitis C infections. It is also being studied in the treatment and prevention of cancer. It is…
A synthetic, non-recombinant, pegylated, peptidic erythropoiesis stimulating agent. Synthetic peptide-based erythropoiesis stimulating agent binds to and activates the erythropoietin (EPO) receptor on…
A biosimilar of pegfilgrastim, a long-acting pegylated form of recombinant human granulocyte colony-stimulating factor (G-CSF) filgrastim, with hematopoietic activity. In a similar…
A drug used to increase numbers of white blood cells in patients who are receiving chemotherapy. It is a type of colony-stimulating…
