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Penicillamine
Pronunciation
Definition 1
A drug that removes copper from the body and is used to treat diseases in which there is an excess of copper. It is also being studied as a possible angiogenesis inhibitor in the treatment of brain tumors. (NCI Dictionary)
Definition 2
A beta dimethyl analog of the amino acid cysteine. As a degradation product of penicillin antibiotics, penicillamine chelates with heavy metals and increases their urinary excretion. Possessing antineoplastic properties, penicillamine induces apoptosis by a p53-mediated mechanism and inhibits angiogenesis by chelating with copper, a cofactor for angiogenesis. (NCI Thesaurus)
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