Percent Free Prostate-Specific Antigen

Definition 1

PSA circulates in the blood in two forms: free or attached to a protein molecule. With benign prostate conditions, there is more free PSA, while cancer produces more of the attached form. A more accurate predictor of cancer than either a patient's age or his total PSA level. (from Cancer Information Service) (NCI Thesaurus)

Definition 2

The amount of the protein prostate-specific antigen (PSA) in the blood that is not attached to other proteins. It is compared with the amount of PSA in the blood that is attached to other proteins. The amount of free PSA is higher in men with benign prostatic hyperplasia (BPH).The amount of PSA attached to other proteins is higher in men with prostate cancer. (NCI Dictionary)

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