Health / Medical Topics

    Perillyl alcohol

    Pronunciation

    Definition 1

    A substance that is being studied in the prevention of cancer. It belongs to the family of plant drugs called monoterpenes. (NCI Dictionary)

    Definition 2

    A naturally occurring monoterpene related to limonene with antineoplastic activity. Perillyl alcohol inhibits farnesyl transferase and geranylgeranyl transferase, thereby preventing post-translational protein farnesylation and isoprenylation and activation of oncoproteins such as p21-ras, and arresting tumor cells in the G1 phase of the cell cycle. (NCI Thesaurus)

    Definition 3

    A terpene with two isoprene units forming a ring and with a hydroxyl group attached to the head methyl group. The chemical structure is CC(=C)C1CCC(=CC1)CO. (NCI Thesaurus/CRCH)




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