Periodic Acid Schiff Staining Method

Definition 1

This is an all-round useful stain for many things, including glycogen, mucin, mucoprotein, glycoprotein, as well as fungi. The reaction is based on the oxidation of glycol group to aldehydes by periodate. The schiff's reagent selectively stains the aldehydes to a rose pink color. PAS is useful for outlining tissue structures--basement membranes, capsules, blood vessels, etc. (NCI Thesaurus)

Definition 2

A microscopy staining method that utilizes Schiff's reagent, a solution composed of pararosanilin treated with sulfurous acid, which selectively reacts with and stains aldehydes pink to determine the presence of glycogen, mucin, mucoprotein, glycoprotein, as well as fungi. Periodic Acid Schiff staining is useful for outlining tissue structures such as basement membranes, capsules and blood vessels. (NCI Thesaurus/CDISC)

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