| Health / Medical Topics |
Peripheral Blood Lymphocyte Vaccine
A class of vaccines with potential antineoplastic activity. Peripheral blood lymphocytes (PBL) are first harvested from a cancer patient and induced to express a particular tumor-associated antigen or multiple antigens. Autologous vaccination with activated PBL may stimulate the host immune system to produce antibodies and/or mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the antigen(s), resulting in decreased tumor growth. (NCI Thesaurus)
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