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Peripheral Blood Stem Cell Transplantation
Definition 1
Similar to bone marrow transplantation, peripheral stem cell transplantation is a method of replacing the blood-forming cells lost due to high-dose chemotherapy, and possibly radiation therapy, used to destroy leukemia cells. Certain immature circulating blood cells, similar to stem cells in the bone marrow, are removed before treatment. The cells are then given to the patient after treatment to help the bone marrow recover and continue producing healthy blood cells. Transplantation may be autologous (the patient's own blood cells are used), allogeneic (blood cells are donated by someone else), or syngeneic (blood cells are donated by an identical twin). (NCI Thesaurus)
Definition 2
A method of replacing blood-forming cells destroyed by cancer treatment. Immature blood cells (stem cells) in the circulating blood that are similar to those in the bone marrow are given to the patient after treatment. This helps the bone marrow recover and continue producing healthy blood cells. Transplantation may be autologous (an individual's own blood cells saved earlier), allogeneic (blood cells donated by someone else), or syngeneic (blood cells donated by an identical twin). (NCI Dictionary)
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