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PEROXIDASE
Pronunciation (US): | (GB): |
I. (noun)
Sense 1
Meaning:
Any of a group of enzymes (occurring especially in plant cells) that catalyze the oxidation of a compound by a peroxide
Classified under:
Hypernyms ("peroxidase" is a kind of...):
oxidase (any of the enzymes that catalyze biological oxidation)
Domain category:
flora; plant; plant life ((botany) a living organism lacking the power of locomotion)
Hyponyms (each of the following is a kind of "peroxidase"):
glutathione peroxidase (an enzyme in the body that is a powerful scavenger of free radicals)
horseradish peroxidase (an enzyme used in immunohistochemistry to label antigens and their antibodies)
Context examples:
Glutathione peroxidase 1 (203 aa, ~22 kDa) is encoded by the human GPX1 gene.
(Glutathione Peroxidase 1, NCI Thesaurus)
Briefly, sequence-specific probes are hybridized to cells fixed on slides and the sequestered probe is visualized by a peroxidase reaction.
(Chromogenic In Situ Hybridization, NCI Thesaurus)
Ebselen acts as a glutathione peroxidase mimetic and is thereby able to prevent cellular damage induced by reactive oxygen species (ROS).
(Ebselen, NCI Thesaurus)
Free selenium is incorporated into selenocysteine, an amino acid found in more than thirty selenoproteins including the glutathione peroxidases (GPx) enzymes, thioredoxin reductase (TR) and the iodothyronine deiodinase enzymes.
(DL-Selenomethionine, NCI Thesaurus)
This agent also upregulates the expression of transcription coactivator PGC-1alpha and modulates hepatic enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), superoxide dismutase and glutathion peroxidase.
(Diammonium Glycyrrhizinate, NCI Thesaurus)
Glutathione peroxidase (GPx), for example, removes peroxides using glutathione as a reducing agent, and glutathione reductase (GSR) regenerates reduced glutathione.
(Free Radical Induced Apoptosis Pathway, NCI Thesaurus/BIOCARTA)
As a trace mineral that is toxic in high doses, selenium is a cofactor for glutathione peroxidase, an anti-oxidant enzyme that neutralizes hydrogen peroxide.
(L-Selenomethionine, NCI Thesaurus)
An immunoassay utilizing an antibody labeled with an enzyme marker such as horseradish peroxidase.
(ELISA, NLM, Medical Subject Headings)
Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is a component of many enzymes such as catalase, peroxidase, and cytochromes.
(Ferrous sulfate, NCI Thesaurus)
Important in transport of oxygen by hemoglobin to the tissues, iron is also found in myoglobin, transferrin, and ferritin, and is as a component of many enzymes such as catalase, peroxidase, and cytochromes.
(Ferrous Gluconate, NCI Thesaurus)