Health / Medical Topics |
Phase I/II clinical trial
Pronunciation
A study that tests the safety, side effects, and best dose of a new treatment. Phase I/II clinical trials also test how well a certain type of cancer or other disease responds to a new treatment. In the phase II part of the clinical trial, patients usually receive the highest dose of treatment that did not cause harmful side effects in the phase I part of the clinical trial. Combining phases I and II may allow research questions to be answered more quickly or with fewer patients. (NCI Dictionary)
YOU MAY ALSO LIKE
The first step in testing a new treatment in humans. These studies test the best way to give a new treatment (for…
Any natural or synthetic substance that inhibits the activity of any phase I metabolic enzyme. The cytochrome P450 (CYP450) mono-oxygenase family of…
A process in which the liver uses one of two major enzyme pathways to change a toxic substance, such as an anticancer…
The first step in testing a new treatment in humans. A phase I study tests the safety, side effects, best dose, and…
Select candidate vaccines or concepts suitable for Phase I and Phase II trials and conduct these trials.
A coded value specifying the phase for a study.