| Health / Medical Topics |
Phosphatidylinositol 4,5-bisphosphate
Phosphatidylinositol 4,5-Diphosphate; PIP2. A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate (IP3) and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994) (NCI Thesaurus)
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