Health / Medical Topics |
PIK3R2/USP8 Fusion Gene
A fusion gene that results from a rearrangement of chromosomes 15 and 19 which fuses the 5' end of the PIK3R2 gene to the 3' end of the USP8 gene. This rearrangement may be associated with chronic myeloproliferative disorder. (NCI Thesaurus)
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Human PIK3R2 wild-type allele is located within 19q13.2-q13.4 and is approximately 17 kb in length. This allele, which encodes phosphatidylinositol 3-kinase regulatory…
This gene is involved in the regulation of receptor tyrosine kinase activity.
Human PIK3R1 wild-type allele is located in the vicinity of 5q13.1 and is approximately 86 kb in length. This allele, which encodes…
This gene is involved in phosphoinositol signaling.
Human PIK3CG wild-type allele is located in the vicinity of 7q22.3 and is approximately 42 kb in length. This allele, which encodes…
This gene is involved in cell adhesion, signal transduction and maintenance of the structural and functional integrity of epithelia.