Health / Medical Topics

    PIK3R2/USP8 Fusion Protein

    A fusion protein encoded by the PIK3R2/UPS8 fusion gene. This protein is comprised of most of the phosphatidylinositol 3-kinase regulatory subunit alpha protein, excluding the second SH2 domain, fused to the C-terminus of the ubiquitin carboxyl-terminal hydrolase 8 protein. (NCI Thesaurus)




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    This gene is involved in the regulation of receptor tyrosine kinase activity.
    Human PIK3R1 wild-type allele is located in the vicinity of 5q13.1 and is approximately 86 kb in length. This allele, which encodes…
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