| Health / Medical Topics |
PITX2 wt Allele
Human PITX2 wild-type allele is located within 4q25-q27 and is approximately 25 kb in length. This allele, which encodes pituitary homeobox 2 protein, plays a role in both the modulation of transcription and the regulation of pancreatic development. Mutations in the gene are associated with Rieger syndrome type 1, iridogoniodysgenesis type 2, Peters anomaly, and ring dermoid of cornea. (NCI Thesaurus)
YOU MAY ALSO LIKE
Many transcription factors play essential roles in normal development by determining the proliferation and differentiation of cells. The coordinated transcriptional control…
This gene is involved in both the development of the pancreas and transcriptional regulation.
Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it…
A tumor that forms in the pituitary gland. The pituitary gland is a pea-sized organ at the base of the brain. It…
A meningioma that affects the pituitary stalk.
Grafting of pituitary tissue between genetically identical individuals.
