| Health / Medical Topics |
Pivampicillin Hydrochloride
The hydrochloride salt form of a semisynthetic, orally active pivalate ester of ampicillin with antibacterial activity. Upon absorption, pivampicillin is hydrolyzed into its active form ampicillin by esterases. Ampicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis. (NCI Thesaurus)
YOU MAY ALSO LIKE
A semisynthetic, orally active pivalate ester of ampicillin with antibacterial activity. Upon absorption, pivampicillin is hydrolyzed into its active form ampicillin by…
An acyloxyalkyl ester prodrug of butyric acid. Pivaloyloxymethylbutyrate inhibits histone deacetylase, resulting in cell differentiation, cell growth inhibition, and apoptosis.
A rare cutaneous disorder of unknown etiology characterized by the presence of reddish-orange scaly plaques, palmoplantar keratoderma, keratotic follicular papules, and confluent…
A mild, self-limited skin disorder that is most commonly seen in children and young adults. It is characterized by an initial large…
A rare skin disorder of unknown etiology that is considered to be a more severe form of pityriasis lichenoides. It is characterized…
A rare cutaneous disorder of unknown etiology that can present either as an acute condition, with multiple papular lesions which become vesicular…
