Health / Medical Topics |
Plasminogen Activator Interaction
Plasminogen Activator Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction with heterogeneous group of widely expressed lysosomal and secreted serine proteases having fibrin-binding activity that convert plasminogen to fibrinolytic plasmin. Inhibited by PAI-1, encoded by the PLAT Gene (Peptidase S1 Family), and cleaved by plasmin, tissue kallikrein, or factor XA to disulfide-linked A/B chains, tissue-type plasminogen activator plays a role in cell migration and tissue remodeling. (NCI Thesaurus)
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The determination of the amount of plasminogen activator inhibitor-1 present in a sample.
The determination of the amount of plasminogen activator inhibitor-1 antigen present in a sample.
Plasminogen activator inhibitor 2 (415 aa, ~47 kDa) is encoded by the human SERPINB2 gene. This protein plays a role in the…
Plasminogen activator inhibitor 1 (402 aa, ~45 kDa) is encoded by the human SERPINE1 gene. This protein plays a role in both…
A member of the serpin family of serine protease inhibitor proteins that inhibits plasminogen activator type proteases.
A family of serine proteases that catalyze the proteolytic conversion of plasminogen to plasmin.