| Health / Medical Topics |
PML/RARA Fusion Gene
A fusion gene that results from a chromosomal translocation t(15;17)(q22;q21) which fuses the first 3 exons of the PML gene with the last 7 exons of the RARA gene. This fusion is associated with acute promyelocytic leukemia. Three transcript variants are possible based on the three breakpoint clusters in the PML gene. (NCI Thesaurus)
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Expression of a fusion protein that results from a fusion of the human genes PML and RARA.
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