| Health / Medical Topics |
pNGVL3-hICD Vaccine
A plasmid DNA cancer vaccine encoding the intracellular domain (ICD) of the HER-2/neu proto-oncogene. Upon administration and after cellular uptake by skin or muscle cells, the pNGVL3-hICD vaccine plasmid expresses the HER-2/neu protein, which, after intracellular processing, may elicit both antigen-specific cytotoxic T-lymphocyte (CTL) and humoral immune responses against tumor cells expressing HER-2. The HER-2/neu ICD protein is highly immunogenic and, as a subdominant epitope, may be associated with decreased immune tolerance. (NCI Thesaurus)
YOU MAY ALSO LIKE
A genus of enveloped, spherical viruses in the family Paramyxoviridae. The genome is composed of a linear single-strand of negative sense…
A subfamily of Paramyxoviridae which includes human respiratory syncytial virus.
Abnormal presence of air in the pleural cavity.
Free air within the peritoneal cavity.
The presence of air in the pericardial cavity. Causes include chest injury in adults, and respiratory distress syndrome in infants.
Inflammation of the lungs. This may be caused by disease, infection, radiation therapy, allergy, or irritation of lung tissue by inhaled…
