Health / Medical Topics |
POLR2A wt Allele
Human POLR2A wild-type allele is located in the vicinity of 17p13.1 and is approximately 30 kb in length. This allele, which encodes DNA-directed RNA polymerase II largest subunit protein, is involved in the transcription of DNA into RNA precursors. (NCI Thesaurus)
YOU MAY ALSO LIKE
This gene plays a role in DNA-dependent transcription of RNA.
An orally available fumarate salt form of CFI-400945, a polo-like kinase 4 (PLK4) inhibitor with potential antineoplastic activity. Upon oral administration, polo-like…
An orally bioavailable, small-molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor NMS-1286937 selectively inhibits PLK1, inducing…
An orally bioavailable Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor MK1496 selectively inhibits Plk1, inducing selective…
A small molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor GSK461364 selectively inhibits Plk1, inducing selective…
Members of the polo subfamily of protein kinases appear to play pivotal roles in cell division and proliferation. These include mammalian Plk,…